{"id":3767,"date":"2025-03-21T10:33:38","date_gmt":"2025-03-21T10:33:38","guid":{"rendered":"https:\/\/integrativa.pt\/?p=3767"},"modified":"2025-10-12T17:36:18","modified_gmt":"2025-10-12T17:36:18","slug":"the-role-of-physical-exercise-in-regulating-inflammation-and-strengthening-the-immune-system","status":"publish","type":"post","link":"https:\/\/integrativa.pt\/en\/o-papel-do-exercicio-fisico-na-regulacao-da-inflamacao-e-no-fortalecimento-do-sistema-imunitario\/","title":{"rendered":"The Role of Physical Exercise in Regulating Inflammation and Strengthening the Immune System"},"content":{"rendered":"<div class=\"wpb-content-wrapper\" id=\"wpb-content-root\"><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>The practice of physical exercise not only brings benefits to cardiovascular and muscular health, but also plays a fundamental role in inflammation regulation and strengthening the immune system. One of the main reasons for this positive effect lies in the release of interleukin-6 (IL-6) by muscles during physical activity.<\/p>\n<p><strong>How Exercise Reduces Inflammation<\/strong><\/p>\n<p>During physical exertion, muscles release IL-6, a myokine that has a direct impact on the body's inflammatory response. This substance promotes the production of IL-10, an anti-inflammatory cytokine, while simultaneously inhibiting IL-1\u03b2, an inflammatory mediator associated with various chronic diseases. Thus, IL-6 acts as a true modulator of inflammation, helping to reduce inflammatory processes that can cause pain and other health problems.<\/p>\n<p><strong>Impact on the Immune System<\/strong><\/p>\n<p>In addition to its anti-inflammatory effect, IL-6 stimulates the production of neutrophils, cells essential for the body's defence against infections. This enhanced immune response contributes to a better balance in the functioning of the immune system, helping to reduce the excessive production of self-reactive bodies. This is particularly relevant for individuals with autoimmune diseases, where the immune system attacks the body's own healthy tissues.<\/p>\n<p><strong>Long-Term Benefits<\/strong><\/p>\n<p>Maintaining an active lifestyle can have profound effects on the prevention and management of various inflammatory and immunological conditions. People who exercise regularly have a lower risk of developing chronic diseases, such as arthritis, type 2 diabetes, and cardiovascular diseases, largely due to the anti-inflammatory effect of movement.<\/p>\n<p>Furthermore, exercise also contributes to general well-being, helping to reduce stress and improve sleep quality, factors that also influence inflammation regulation and immune health.<\/p>\n<p><strong>What is the most suitable type of exercise?<\/strong><\/p>\n<p>To obtain these benefits, intense exercise is not necessary. Moderate-intensity activities, such as walking, light jogging, yoga, or resistance training, are sufficient to stimulate the release of IL-6 and strengthen the immune system. The most important thing is to maintain regularity and adapt the exercise to your needs and limitations.<\/p>\n<p>Science, such as that in Clinical Psychoneuroimmunology, has demonstrated that physical exercise goes far beyond muscle strengthening or weight loss. Its influence on reducing inflammation and modulating the immune system is a valuable asset for overall health. Adopting an active lifestyle can be a simple and effective strategy for improving quality of life and preventing various diseases. Therefore, regardless of age or physical condition, moving is one of the best ways to take care of your health!<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid vc_custom_1680169461443\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element  vc_custom_1742553129083\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p style=\"text-align: right;\"><strong>David Brand\u00e3o <\/strong>Physiotherapist, Osteopath and Clinical Psychoneuroimmunology Specialist<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid vc_custom_1680169461443\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element  vc_custom_1680169468507\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><a title=\"Home\" href=\"https:\/\/integrativa.pt\/en\/\"><strong>Integrativa<\/strong><\/a> | Health and well-being as a lifestyle<\/p>\n\n\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"wpb_text_column wpb_content_element  vc_custom_1689951960351\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h6>This website and its content are for information purposes only and are not a substitute for medical or health professional advice. Each person's treatment should be individualised and guided by health professionals. Do not make any changes to your treatment without contacting the doctor or health professional accompanying you.<\/h6>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner vc_custom_1678987635945\"><div class=\"wpb_wrapper\"><div class=\"vc_separator wpb_content_element vc_separator_align_center vc_sep_border_width_1 vc_sep_pos_align_center wpb_content_element vc_separator-has-text\"   style=\"width: 100%;\"><span class=\"vc_sep_holder vc_sep_holder_l\"><span style=\"border-top-color:#1b9193;\" class=\"vc_sep_line\"><\/span><\/span><h4>Related articles<\/h4><span class=\"vc_sep_holder vc_sep_holder_r\"><span style=\"border-top-color:#1b9193;\" class=\"vc_sep_line\"><\/span><\/span>\n<\/div><style type=\"text\/css\" 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.blog-carousel-shortcode.blog-carousel-shortcode-id-6445186a3749ae3263f11e7907d520e6.reposition-arrows .owl-nav .owl-next {\n    transform: translateY(-50%);\n    margin-top: 0px;\n  }\n}<\/style><div class=\"owl-carousel blog-carousel-shortcode dt-owl-carousel-call blog-carousel-shortcode-id-6445186a3749ae3263f11e7907d520e6 classic-layout-list scale-img dt-icon-bg-off dt-arrow-border-on dt-arrow-hover-border-on meta-info-off bullets-small-dot-stroke reposition-arrows arrows-bg-on disable-arrows-hover-bg arrows-hover-bg-on\" data-scroll-mode=\"1\" data-col-num=\"3\" data-wide-col-num=\"4\" data-laptop-col=\"3\" data-h-tablet-columns-num=\"3\" data-v-tablet-columns-num=\"2\" data-phone-columns-num=\"1\" data-auto-height=\"true\" data-col-gap=\"30\" data-stage-padding=\"0\" data-speed=\"600\" data-autoplay=\"false\" data-autoplay_speed=\"6000\" data-arrows=\"true\" data-bullet=\"false\" data-next-icon=\"icon-ar-017-r\" data-prev-icon=\"icon-ar-017-l\"><article class=\"post post-3824 type-post status-publish format-standard has-post-thumbnail hentry category-4-pilares-da-saude category-osteopata-david-brandao category-osteopatia-integrativa-osteopatia category-psiconeuroimunologia category-sono category-sono-4-pilares-da-saude tag-fisioterapia tag-osteopatia tag-pilates-clinico category-35 category-33 category-34 category-48 category-36 category-37 description-off\" data-name=\"Melatonina, luz solar e regula\u00e7\u00e3o do sono: compreender a rela\u00e7\u00e3o\" data-date=\"2025-08-21T11:16:57+00:00\">\n\n<div class=\"post-thumbnail-wrap\">\n\t<div class=\"post-thumbnail\">\n\t\t\n\t\t\n\t\t<a href=\"https:\/\/integrativa.pt\/en\/melatonina-luz-solar-e-regulacao-do-sono-compreender-a-relacao\/\" class=\"post-thumbnail-rollover layzr-bg\" ><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me owl-lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20768%20512&#39;%2F%3E\" data-src=\"https:\/\/integrativa.pt\/wp-content\/uploads\/2025\/08\/Integrativa-2-768x512.webp\" data-srcset=\"https:\/\/integrativa.pt\/wp-content\/uploads\/2025\/08\/Integrativa-2-768x512.webp 768w, https:\/\/integrativa.pt\/wp-content\/uploads\/2025\/08\/Integrativa-2-1152x768.webp 1152w\" loading=\"eager\" style=\"--ratio: 768 \/ 512\" sizes=\"(max-width: 768px) 100vw, 768px\" alt=\"\" title=\"Integrative (2)\" width=\"768\" height=\"512\"  \/><\/a>\t<\/div>\n<\/div>\n\n\n<div class=\"post-entry-content\">\n\n\t<h3 class=\"entry-title\">\n\t\t<a href=\"https:\/\/integrativa.pt\/en\/melatonina-luz-solar-e-regulacao-do-sono-compreender-a-relacao\/\" title=\"Melatonin, sunlight and sleep regulation: understanding the relationship\" rel=\"bookmark\">Melatonin, sunlight and sleep regulation: understanding the relationship<\/a>\n\t<\/h3>\n\n\t\n\t\n\t\n<a href=\"https:\/\/integrativa.pt\/en\/melatonina-luz-solar-e-regulacao-do-sono-compreender-a-relacao\/\" class=\"post-details 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aria-hidden=\"true\"><\/i><\/a>\n\n<\/div><\/article><\/div><\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Physical exercise not only benefits cardiovascular and muscular health, but also plays a fundamental role in regulating inflammation and strengthening the immune system. One of the main reasons for this positive effect lies in the release of interleukin-6 (IL-6) by the muscles during physical activity. How Exercise Reduces...<\/p>","protected":false},"author":1,"featured_media":4670,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[35,38,34,48],"tags":[4,27,8],"class_list":["post-3767","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-4-pilares-da-saude","category-atividade-fisica","category-osteopatia-integrativa-osteopatia","category-psiconeuroimunologia","tag-fisioterapia","tag-osteopatia","tag-pilates-clinico","category-35","category-38","category-34","category-48","description-off"],"_links":{"self":[{"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/posts\/3767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/comments?post=3767"}],"version-history":[{"count":0,"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/posts\/3767\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/media\/4670"}],"wp:attachment":[{"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/media?parent=3767"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/categories?post=3767"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/integrativa.pt\/en\/wp-json\/wp\/v2\/tags?post=3767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}